By clicking on the PDB logo, you will be redirected to the Protein Data Bank website presenting the extensive list of the structures we solved @IBCP. |
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Deciphering key features in protein structures with the new ENDscript server |
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ENDscript 2 is a friendly webserver for extracting and rendering a comprehensive analysis of primary to quaternary protein structure information in an automated way. This major upgrade has been fully re-engineered to enhance speed, accuracy and usability with interactive 3D visualization. It takes advantage of the new version 3 of ESPript, our well-known sequence alignment renderer, improved to handle a large number of data with reduced computation time. From a single PDB entry or file, ENDscript produces high quality figures displaying multiple sequence alignment of proteins homologous to the query, colored according to residue conservation. Furthermore, the experimental secondary structure elements and a detailed set of relevant biophysical and structural data are depicted. All this information and more are now mapped on interactive 3D PyMOL representations. Thanks to its adaptive and rigorous algorithm, beginner to expert users can modify settings to fine-tune ENDscript to their needs. ENDscript has also been upgraded as an open platform for the visualization of multiple biochemical and structural data coming from external biotool webservers, with both 2D and 3D representations. ENDscript 2 and ESPript 3 are freely available at http://endscript.ibcp.fr and http://espript.ibcp.fr . Robert X & Gouet P (2014). Nucleic Acids Res. 42:W320-4 |
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Internal IBCP |
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Vincent ChaptalMMSB, CNRS – Université de Lyon Christophe GrangeasseMMSB, CNRS – Université de Lyon Guillaume LaunayMMSB, CNRS – Université de Lyon Juliette MartinMMSB, CNRS – Université de Lyon Cédric OrelleMMSB, CNRS – Université de Lyon Bernard VerrierLBTI, CNRS – Université de Lyon |
External |
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Guzmán Álvarez TouronUniversidad de la República - Paysandú, Uruguay Yannick BlanchardViral Genetics and Biosafety - ANSES Ploufragan, France Laure GuyÉcole Normale Supérieure - Lyon, France Xavier HanoulleNMR & Molecular Interactions - CNRS Villeneuve d'Ascq, France Renaud MahieuxInternational Center for Infectiology Research - Lyon, France Vincent ParissiFundamental Microbiology and Pathogenicity Lab - CNRS Bordeaux, France Stéphane PaulGroupe sur l'Immunité des Muqueuses et Agents Pathogènes - Faculté de Médecine de Saint-Etienne, France Corinne RonfortPathogenicity and Virus Vaccine Lab - INRA Grenoble, France Maria-Cristina de RosaInstitute of Chemistry of Molecular Recognition - Rome, Italy Guy SchoehnInstitute of Structural Biology - Grenoble, France Vladimir ShevchikMicrobiology, Adaptation and Pathogenesis Lab - INSA Villeurbanne, France |
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